Relora Mechanism of Action

Relora® is a natural stress management ingredient that helps control stress-related eating and has the added value of being non-sedating. In central nervous system receptor binding assays the plant extracts in Relora® binds to several important targets associated with stress. It does not bind to the benzodiazepine receptors that would cause sedation, yet has the relaxing qualities that have been demonstrated in both animal and human studies. In addition, it normalizes hormone levels associated with stress-induced weight gain and eating behavior. Stress has been shown to play a significant role in a variety of conditions. A large percentage of overweight adults have excessive abdominal fat due to stress-related over eating. Relora® appears to maintain healthy hormone levels in stressed individuals and act as an aid in controlling weight and stress-related eating.In human studies Relora™ was shown to be a safe, effective, rapid-acting, non-sedating supplement, which promoted relaxation, calm and a feeling of well-being. Relora has also been demonstrated to lower Cortisol levels, the hormone released during periods of stress. Elevated Cortisol levels are thought to cause various health problems including a compromised immune system, high blood pressure, depression, insomnia, loss of vitality and weight gain*.* SEPTEMBER 2004 Pharmaceuticals, Inc. has been issued a patent on Magnolia, a key component in the company's all natural, anti-stress ingredient Relora®.

The patented methodology, US 6,582,735, relates to the use of Relora® for weight loss associated with stress and a stress-related condition known as "metabolic syndrome."