About our Mangosteen Elixir®

Mangosteen Elixir® is made with hand-harvested, cold-pressed mangosteen. To the pure mangosteen juice we add our own proprietary blend of organic noni juice, goji juice, organic black cherry juice, organic cranberry juice, blueberry juice, organic red raspberry juice, pomegranate juice and black elderberry juice. Is a Synergy Juice Blend made from nine high ORAC rated, antioxidant-rich super fruits. It's perfect for the entire family and it tastes absolutely fabulous!

What Benefits may I see from Mangosteen Elixir®:

• Supports Healthy Weight Loss
• Supports Health Cholesterol Levels
• Supports Healthy Joints and Skin
• Supports a Healthy Gastrointestinal Tract
• Supports Healthy Connective Tissue
• Supports Healthy Cognitive Function
• Supports a Healthy Cardiovascular System
• Supports a Healthy Immune System

"My own personal research has revealed that mangosteen is being widely used by health practitioners worldwide for a variety of body ailments such as eczema, psoriasis, diabetes, weight loss, nerve pain, infections, arthritis, anxiety, depression, dementia, cancer and many others." (Dr. E)

Mangosteen Elixir® Ingredients:

Our Mangosteen Elixir® is a synergistic blend of pure, hand-harvested, cold-pressed mangosteen juice (Garcinia mangostana) and mangosteen puree (mangosteen is ~60% by volume), organic goji (Lycium barbarum) juice, pomegranate (Punica granatum), organic black cherry (Prunus sertin), orgainc blueberry (Vaccinium myrtillus) juice, organic cranberry (Vaccinium macrocatpon) juice, and apple juice (Fruit) (Malus domestica) juice blend (~40% by volume).

Our juice includes the sweet fleshy pulp of the interior of the mangosteen fruit as well as the xanthone-rich pericarp.

Pulp (n.): soft of fleshy plant tissue such as the inner part of a fruit or vegetable.

Pericarp (n.): the part of a fruit that surround the seed or seeds, including the skin or rind.

Xanthone (n.): C₁₃H₈O₂ a unique class of biologically active compounds possessing numerous bioactive capabilities, such as high antioxidant properties.

Origin:

The exact place of origin of mangosteen (Garcinia mangostanaL.) is unknown but research indicates it was probably somewhere in the Malay Archipelago. Native species may still be found growing wild on some islands. The majority of today s mangosteen cultivation occurs in Thailand with smaller areas of cultivation throughout Southeast Asia. Mangosteen has proved itself a difficult plant to domesticate. It has been planted throughout the warm/humid climate regions of the world with little success in any mass cultivation. This is due to the mangosteen s inability to acclimate itself to any other region than its place of origin. The result of this limited cultivation, combined with the mangosteen plant being very slow growing, is expressed it the high price for the pure finished product.

Mangosteen is composed of these substances:

There is a big buzz in the medical and holistic community these days and it s all because of a fairly recent discovery. This discovery is the phenomenal health benefits the human body derives from a phytochemical class known as xanthones. Over 200 xanthones have been identified in nature, with each one possessing its own unique effects on the body. Xanthones are contained within a large family of compounds known as phenols and within this grouping can also found bioflavonoids, anthocyanins, and proanthocyanidins (OPCs). Xanthones are the primary active phytochemical class found in the Mangosteen fruit (Garcinia mangostanaL.). Science has crowned the king of xanthones and it s the mangosteen fruit, with over 40 xanthones identified in the pericarp, more commonly known as the rind, making the mangosteen the most abundant source of xanthones in the world. Of these 40 or so xanthones only six of the xanthones have been studied in depth - with much excitement, I would like to add. These xanthones isolated are Mangostin, Mangostanol, y-Mangostin, Gartanin, Garcinone B and Garcinone E. Researches still don t completely understand how the xanthones in the mangosteen fruit exert such a favorable impact on human health. Researches though, do validate the fact that the mangosteen possesses powerful healing properties that surpass many man made substances.

Conclusion:

In conclusion, over the months and years to come the scientific community will continue to unlock more secrets still to be found inside the mangosteen fruit. With each new clinical study we move another step closer to validating its main phytonutrients, mangosteen xanthones, for the treatment and prevention of disease. Today we can all reap the benefits from nature and science in the form of our Synergy Juice Blend of nine high ORAC rated, antioxidant-rich fruits that are Mangosteen Elixir®. It tastes terrific and it s terrific for you!

Published research involving chemical constituents of mangosteen:

• Anti-Fungal 1, 2
• Anti-Histamine (histamine H1 receptor antagonist in vitro) 3, 4, 5, 6
• Anti-Inflammatory (Prostaglandin E2 and Cyclooxygenase [COX-1 and 2] synthesis inhibition in vitro) 5, 6,
• Anti-Bacterial/Microbial 1, 7, 8, 9 (Mycobacterium tuberculosis in vitro) 10 (Propionibacterium acnes and Staphylococcus epidermidis) 11
• Anti-Oxidant/Free Radical Scavenging (more potent than BHA or vitamin E), (LDL-cholesterol oxidation-inhibiting in vitro) 12, 15, 17, 19
• Anti-Viral in vitro (HIV-1 protease) 13
• Cancer Cell Growth-Inhibiting (Breast, Stomach, Liver, Lung [cell lines25] and Leukemia cell lines in vitro) 14, 15, 16
• Immune-Stimulating (phagocytic cells) 18
• LDL-Cholesterol Oxidation-Inhibiting in vitro 19

References:

1. Sundaram B.M., et al. Antimicrobial activities of (Garcinia mangostana L.). Planta Med. 1983; 48:59-60.
2. Begum N., et al. Anti-ulcer and antimicrobial activities of gartanin, xanthone from (Garcinia mangostana L.). Linn. Bull Islam Med. 1982; 2:518-21.
3. Chairungsrilerd N., et al. Histaminergic and serotonergic receptor-blocking substances from the medicinal plant (Garcinia mangostana L.). Planta Med. 1996; 62:471-2.
4. Chairungsrilerd N., et al. Pharmacological properties of a-mangostin, a novel histamine H1 receptor antagonist. Eur J Pharmacol. 1996; 314:351-6.
5. Nakatani K., et al. Inhibition of cyclooxygenase and prostaglandin E2 synthesis by g-mangostin, a xanthone derivative in mangosteen, in C6 rat glioma cells. Biochem Pharmacol. 2002; 63:73-9.
6. Nakatani K., et al. Inhibitions of histamine release and prostaglandin E2 synthesis by mangosteen, a Thai medicinal plant. Biol Pharm Bull. 2002; 25:1137-41.
7. Iinuma M., et al. Antibacterial activity of xanthones from Guttiferaeous plants against methicillin - resistant Staphylococcus aureus. J Pharm Pharmacol. 1996; 48:861-5.
8. Mahabusarakam W., et al. Antimicrobial activities of chemical constituents from (Garcinia mangostana L.). Linn. J Sci Soc Thailand. 1986; 12:239-42.
9. Sindermsuk J, et al. Comparison of the efficiency in diarrhea treatment between the leaf of guava (Psidium guajava L.), and the fruit hull of mangosteen (Garcinia mangostana L.). Mahidol Univ J Pharm Sci. 1989; 16:32-5.
10. Suksamrarn S, et al. Antimycobacterial activity of prenylated xanthones from the fruit of (Garcinia mangostana L.). Chem Pharm Bull. 2003; 51:857-9.
11. Chomnawang M.T., et al. Antimicrobial effects of Thai medicinal plants against acne-inducing bacteria. J Ethnopharmacol. 2005; 101(1-3):330-3.
12. Fan CT, Su JD. Antioxidative mechanism of isolated components from methanol extract of fruit hulls of (Garcinia mangostana L.). J Chin Agric Chem Soc. 1997; 35:540-51.
13. Chen SX, et al. Active constituents against HIV-1 protease from (Garcinia mangostana L.). Planta Med. 1996; 62:381-2.
14. Matsumoto K, et al. Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines. J Nat Prod. 2003; 66:1124-7.
15. Moongkarndi P., et al. Antiproliferation, antioxidation & induction of apoptosis by Garcinia mangostana (mangosteen) on SKBR3 human breast cancer cell line. J Ethnopharmacol. 2004; 90:161-6.
16. Lim-Sylianco C.Y., et al. Antimutagenic effects of expressions from eighteen medicinal plants. Philippine J Sci. 1986; 115;293-8.
17. Yoshikawa M., et al. [Antioxidant constituents from the fruit hulls of mangosteen (Garcinia mangostana L.) originating in Vietnam]. Yakugaku Zasshi. 1994; 114:129.
18. Chanarat P., et al. Immunopharmacological activity of polysaccharide from the pericap of mangosteen garcinia: Phagocytic intracellular killing activities. J Med Assoc Thai. 1997; 80(suppl.).
19. Williams P., et al. Mangostin inhibits the oxidative modification of human low density lipoprotein. Free Radical Res. 1995; 23:175-84.

Nutrition Facts^#

Serving Size: One (1) Fluid Ounce (30 ml)

Servings Per Container: 32 (946 ml - 908 g)

* Percent Daily Values are based on 2000 Calorie diet. ** Percent Daily Value not established.

# These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested Usage:

Shake gently before opening. As a dietary supplement, take 2-4 tablespoons (1-2 oz.) or more in the morning and/or evening, before meals. The juice may be mixed with water, another juice, or in a smoothie. Please refrigerate after opening.

Safety Information:

This formula does not contain preservatives, solvents, additives, fillers, yeast, wheat, corn, soy, or milk. Always consult with a healthcare professional before using any nutritional supplement or starting any nutritional program. Do not use this product if you have a known allergy to any of the ingredients contained in this product. This product has not been evaluated by the Food and Drug Administration.